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Asian Journal of Urology, 2023, 10(2): 144-150    doi: 10.1016/j.ajur.2021.11.002
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Necrosis zone depth after bipolar plasma vaporization and resection in the human prostate
Clara Breitlinga,Hans Nenningb,Jörg Rasslera*()
aDepartment of Urology, St. Elisabeth Hospital, Leipzig, Germany
bInstitute for Pathology “Am Elsapark”, Leipzig, Germany
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Abstract: 

Objectives: To compare the depth of thermal necrosis after use of bipolar resection and vaporization technique comparing intra-individually bipolar loop and bipolar button electrodes.
Methods: Transurethral resection and vaporization of the prostate was performed in 55 male patients (260 specimens in total). In a standardized procedure, a bipolar resection loop was used for resection, and a bipolar button electrode was used for vaporization. Both electrodes were applied in each patient, either in the left or in the right lateral lobe. The depth of necrotic zones in the resected or vaporized tissue of each patient was measured in a standardized way by light microscopy.
Results: The mean depth with standard deviation of thermal injury caused by the loop electrode was 0.0495±0.0274 mm. The vaporization electrode caused a mean thermal depth with standard deviation of 0.0477±0.0276 mm. The mean difference of necrosis zone depths between the two types of electrodes (PlasmaButton-resection loop) was −0.0018 mm (p=0.691).
Conclusion: For the first time, we present directly measured values of the absolute necrosis zone depth after application of plasma in the transurethral treatment of benign prostatic hyperplasia. The measured values were lower than in all other transurethral procedures. Standardized procedures of measurement and evaluation allow a statistically significant statement that the low necrosis depth in bipolar procedures is independent of the applied electrodes.

Key words:  Transurethral resection of prostate    Bipolar enucleation    Plasma resection    Plasma vaporization    Necrosis depth
收稿日期:  2020-12-21      修回日期:  2021-04-15      接受日期:  2021-06-15      出版日期:  2023-04-20      发布日期:  2023-05-24      整期出版日期:  2023-04-20
引用本文:    
. [J]. Asian Journal of Urology, 2023, 10(2): 144-150.
Clara Breitling,Hans Nenning,Jörg Rassler. Necrosis zone depth after bipolar plasma vaporization and resection in the human prostate. Asian Journal of Urology, 2023, 10(2): 144-150.
链接本文:  
http://www.ajurology.com/CN/10.1016/j.ajur.2021.11.002  或          http://www.ajurology.com/CN/Y2023/V10/I2/144
Parameter Value
Agea, year 71.7±7.1
Group 1b,c 29 (52.7)
Group 2b,c 26 (47.3)
BMIa, kg/m2 26.47±3.99
PSAa, ng/mL 4.69±3.62
Prostate volumea, cm3 70.42±33.76
Intake of 5alpha-reductase inhibitor (dutasteride or finasteride)b 11 (20.0)
Intake of alpha1-inhibitor (tamsulosin)b 13 (23.6)
Intake of combined 5alpha-reductase-inhibitor and alpha1-inhibitorb 5 (9.1)
No prostate-specific medicationb 26 (47.3)
Blood clotting inhibitor (acetylsalicylic acid)b 16 (29.1)
Positive family history for PCab 1 (1.8)
  
  
  
  
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