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Asian Journal of Urology, 2023, 10(1): 89-95    doi: 10.1016/j.ajur.2022.05.011
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A method for reducing thermal injury during the ureteroscopic holmium laser lithotripsy
Xiaoliang Zhuab1,Feiping Lia1,Xixi Hub,Haiping Lia,Songjiang Wua,Haihong Jiangb*()
a Department of Urology and Andrology, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Taizhou, China
b Department of Urology and Andrology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China
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Abstract: 

Objective: Many studies have demonstrated the heat effect from the holmium laser lithotripsy can cause persistent thermal injury to the ureter. The purpose of this study was to elucidate the use of a modified ureteral catheter with appropriate firing and irrigation to reduce the thermal injury to the “ureter” during the ureteroscopic holmium laser lithotripsy in vitro.

Methods:An in vitro lithotripsy was performed using a modified catheter (5 Fr) as the entrance for the irrigation and the holmium laser fiber while using the remaining space in the ureteroscopic channel as an outlet. Different laser power settings (10 W, 20 W, and 30 W) with various firing times (3 s, 5 s, and 10 s) and rates of irrigation (15 mL/min, 20 mL/min, and 30 mL/min) were applied in the experiment. Temperature changes in the “ureter” were recorded with a thermometer during and after the lithotripsy.

Results:During the lithotripsy, the local highest mean temperature was 60.3 °C and the lowest mean temperature was 26.7 °C. When the power was set to 10 w, the temperature was maintained below 43 °C regardless of laser firing time or irrigation flow. Regardless of the power or firing time selected, the temperature was below 43 °C at the rate of 30 mL/min. There was a significant difference in temperature decrease when continuous 3 s drainage after continuous firing (3 s, 5 s, or 10 s) compared to with not drainage (p<0.05) except for two conditions of 0.5 J×20 Hz, 30 mL/min, firing 5 s, and 1.0 J×10 Hz, 30 mL/min, firing 5 s.

Conclusion: Our modified catheter with timely drainage reducing hot irrigation may significantly reduce the local thermal injury effect, especially along with the special interrupted-time firing setting during the simulated holmium laser procedure.

Key words:  Modified catheter    Holmium laser    Lithotripsy    Thermal injury
收稿日期:  2021-12-29      修回日期:  2022-05-07      接受日期:  2022-05-18      出版日期:  2023-01-20      发布日期:  2023-02-06      整期出版日期:  2023-01-20
引用本文:    
. [J]. Asian Journal of Urology, 2023, 10(1): 89-95.
Xiaoliang Zhu,Feiping Li,Xixi Hu,Haiping Li,Songjiang Wu,Haihong Jiang. A method for reducing thermal injury during the ureteroscopic holmium laser lithotripsy. Asian Journal of Urology, 2023, 10(1): 89-95.
链接本文:  
http://www.ajurology.com/CN/10.1016/j.ajur.2022.05.011  或          http://www.ajurology.com/CN/Y2023/V10/I1/89
  
  
  
Flow rate Different power Drainage situation Change in temperature (°C)
3 sa 3sb 5sb 5 sa 3 sb 5sb 10 sa 3 sb 5 sb
15 mL/min 0.5 J×20 Hz Drainage 36.5 26.6 26.6 31.2 28.7 26.8 32.3 28.9 28.0
Not drainage 36.2 36.1 31.0 30.8 32.1 31.8
1.0 J×10 Hz Drainage 32.4 27.2 26.8 30.5 28.0 26.9 39.0 32.7 28.2
Not drainage 32.3 31.9 30.0 29.8 38.5 38.2
1.0 J×20 Hz Drainage 36.7 29.8 26.8 45.0 32.6 27.9 43.7 32.7 28.6
Not drainage 36.0 35.7 44.8 44.5 43.2 43.1
2.0 J×10 Hz Drainage 36.9 26.9 26.6 57.6 38.6 32.1 60.3 39.6 31.8
Not drainage 36.6 36.3 57.4 57.3 60.1 60.1
1.5 J×20 Hz Drainage 55.6 33.6 31.9 58.2 39.2 31.8 59.9 39.1 32.3
Not drainage 55.3 55.2 58.0 57.9 59.7 59.5
3.0 J×10 Hz Drainage 54.1 33.3 27.1 38.7 28.6 26.9 44.0 32.8 28.1
Not drainage 53.9 53.7 38.5 38.4 43.9 43.8
20 mL/min 0.5 J×20 Hz Drainage 34.7 32.1 28.9 36.9 31.6 29.4 37.0 32.7 30.1
Not drainage 34.5 34.0 36.5 36.1 36.9 36.6
1.0 J×10 Hz Drainage 28.8 26.8 26.8 33.8 29.1 26.6 35.1 30.6 28.8
Not drainage 28.6 28.2 33.3 33.1 34.7 34.2
1.0 J×20 Hz Drainage 38.9 31.2 28.2 35.6 28.7 26.8 41.7 33.1 28.1
Not drainage 38.5 38.2 35.4 35.1 41.5 41.3
2.0 J×10 Hz Drainage 43.1 33.5 28.3 41.2 31.6 28.1 45.0 32.7 27.9
Not drainage 43.0 42.8 40.5 39.9 45.0 44.8
1.5 J×20 Hz Drainage 44.7 30.7 27.2 48.2 36.7 31.2 52.3 37.8 31.5
Not drainage 44.5 44.3 48.0 47.9 52.1 50.0
3.0 J×10 Hz Drainage 42.6 31.5 27.8 41.3 33.5 27.1 39.6 31.2 26.8
Not drainage 42.4 42.1 41.0 40.8 39.4 39.1
30 mL/min 0.5 J×20 Hz Drainage 27.8 26.8 26.8 27.1 26.9 26.6 26.7 26.6 26.6
Not drainage 27.6 27.4 27.0 26.8 26.7 26.7
1.0 J×10 Hz Drainage 26.9 26.6 26.6 27.2 26.6 26.6 27.0 26.6 26.6
Not drainage 26.9 26.7 26.7 26.7 27.0 26.8
1.0 J×20 Hz Drainage 35.4 29.1 26.7 36.5 27.9 27.0 36.1 28.2 27.3
Not drainage 35.3 35.1 36.1 35.9 35.8 35.6
2.0 J×10 Hz Drainage 33.6 26.8 26.6 38.7 31.5 27.3 31.1 26.9 26.7
Not drainage 33.5 33.1 38.4 38.2 30.7 30.5
1.5 J×20 Hz Drainage 34.5 28.1 26.9 37.4 31.6 28.6 38.8 30.4 26.9
Not drainage 34.0 33.8 37.2 37.0 38.6 38.4
3.0 J×10 Hz Drainage 39.1 30.6 26.8 38.8 29.3 26.8 36.7 27.6 26.6
Not drainage 39.0 38.8 38.6 38.4 36.5 36.3
  
  
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