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| Impact of coronavirus disease 2019 on semen parameters |
Spyridon P. Basourakos,Peter N. Schlegel*( )
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| Department of Urology, New York Presbyterian Hospital, Weill Cornell Medical Center, New York, NY, USA |
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Abstract Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the virus responsible for the coronavirus disease 2019 (COVID-19) pandemic, has been associated with hypogonadism in patients with acute infection [1]. Angiotensin-converting enzyme 2 (ACE2) receptor is regarded as the viral binding site that facilitates entry into host cells [2]. Therefore, cells that express ACE2, such as spermatogonia, Leydig, and Sertoli cells, may be susceptible to SARS-CoV-2 infection [2]. Testicular damage may possibly be caused directly by viral invasion or secondary to the generalized inflammatory response to COVID-19 [3]. Studies have demonstrated that viral shedding in the semen can take place during the recovery phase, even though SARS-CoV-2 is not present in the semen of all men with COVID-19 [1,4]. Herein, we describe the first case report of a male with longitudinal follow-up who experienced reversible cryptozoospermia after COVID-19.
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Available online: 20 April 2022
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Corresponding Authors:
Peter N. Schlegel
E-mail: pnschleg@med.cornell.edu
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| Characteristic | March 2020 | July 2020 | October 2020 | | Volume, mL | 2.8 | 2.4 | 2.0 | | Total concentration, million/mL | 7.6 | 0.0a | 13.6 | | Percent motile within 1 h, % | 44.0 | 0.0 | 19.0 | | Total motile count, million/specimen | 9.3 | 0.0 | 5.1 | | Progression, % | | | | | Rapid | 36 | 0 | 8 | | Slow | 8 | 0 | 10 | | Static | 56 | 100 | 81 | | White blood cells, million/mL | <1 | <1 | <1 | | pH | 8.0 | 8.5 | 8.1 | | Color | Grey/clear | Grey/clear | Grey/clear | | Viscosity | Normal | +1 | Normal | | Agglutination | None | None | None |
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Semen analysis from March 2020 to October 2020.
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