Total pelvic exenteration and a new model of diversion for giant primitive neuroectodermal tumor of prostate: A case report and review of the literature

doi:10.1016/j.ajur.2019.03.006

Asian Journal of Urology, 2020, 7 (2): 181-185 doi: 10.1016/j.ajur.2019.03.006

Case Report

Total pelvic exenteration and a new model of diversion for giant primitive neuroectodermal tumor of prostate: A case report and review of the literature

Lichen Teng^a,Liangjun Wei^a,Li Li^b,Yongpeng Xu^a,Yongsheng Chen^a,Yan Cao^a,Wentao Wang^a,Changfu Li^a,*(

)

^a Department of Urology, Harbin Medical University Cancer Hospital, Harbin, China
^b Department of Colorectal Surgery, Harbin Medical University Cancer Hospital, Harbin, China

Abstract
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Abstract

The present study reports a rare primitive neuroectodermal tumor (PNET) of prostate. A 27-year-old male was admitted to Harbin Medical University Cancer Hospital (Harbin, China) for dysuria and dyschezia. Magnetic resonance imaging (MRI) revealed a large mass that may involve the bladder and rectum next to the prostate. Histopathological analysis of biopsy of prostate indicated mesenchymal origin tumor, and immunohistochemistric staining confirmed diagnosis of PNET of prostate. En bloc total pelvic exenteration and double barrel sigmoidostomy were performed. Double stomas in the skin incision were used for fecal and urinary diversion, respectively. Short-term outcome is satisfactory, while long-term efficacy remains to be poor. Clinical features of PNET of prostate should be paid much more attention and radical surgery and adjuvant chemotherapy should be recommended.

Key words： Prostate Primitive neuroectodermal tumor Total pelvic exenteration Double barrel sigmoidostomy

Received: 19 November 2017 Available online: 05 April 2019

Corresponding Authors: Changfu Li E-mail: lichangfu2015@sina.com

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	Wentao Wang
	Changfu Li

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Cite this article:

Lichen Teng,Liangjun Wei,Li Li, et al. Total pelvic exenteration and a new model of diversion for giant primitive neuroectodermal tumor of prostate: A case report and review of the literature[J]. Asian Journal of Urology, 2020, 7(2): 181-185.

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http://www.ajurology.com/EN/10.1016/j.ajur.2019.03.006 OR http://www.ajurology.com/EN/Y2020/V7/I2/181

Magnetic resonance image (MRI) of the pelvic region. (A) Coronal T2-weighted scan revealing adherence between mass and base of bladder; (B) Sagital T2-weighted image showing a 84 mm × 78 mm × 72 mm mass replaced prostate gland, which compressed posteriorly rectum and superiorly bladder, respectively; (C) Transverse image showing the mass potentially adhere to pelvic wall.

Double barrel sigmoidostomy: Upper stoma is used for fecal diversion, and lower one is used for urinary diversion.

Reprehensive images with H&E staining and immunohistochemistric staining. (A) H&E staining revealed a lot of small round cells distributed in tumor region (×200); (B) Immunohistochemistric staining demonstrating small round cells positive for CD99 (×200); (C) and (D) reveal small round cells is positive for CD56 and Vim, respectively (×200); (E) and (F) show small round cells negative for CK (×200) and CD34 (×100), respectively.

Clinical characteristics of reported primitive neuroectodermal tumor of prostate cases.

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