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Asian Journal of Urology, 2024, 11(3): 423-428    doi: 10.1016/j.ajur.2023.04.005
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Optimal interval for delayed retrieval surgery with reciprocating morcellators after enucleation of giant prostatic hyperplasia in holmium laser enucleation of the prostate
Fumiyasu Endoa*(),Masaki Shimboa,Kenji Komatsua,Kazuhiro Ohwakib,Kazunori Hattoria
aDepartment of Urology, St. Luke’s International Hospital, 9-1 Akashi-cho, Chuo-ku, Tokyo, Japan
bDepartment of Hygiene and Public Health, Teikyo University School of Medicine Graduate School of Medicine, 2-11-1 Kaga, Itabashi-ku, Tokyo, Japan
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Abstract: 

Objective: The aim of this research was to evaluate the efficiency of reciprocating morcellation for removing giant benign prostatic hyperplasia during holmium laser enucleation of the prostate, investigate whether performing morcellation as a two-stage procedure improves tissue retrieval efficiency, and seek to determine the optimal interval between the two surgeries.

Methods: This study included nine cases of holmium laser enucleation of the prostate with an enucleated prostate weight exceeding 200 g, indicative of substantial prostate enlargement. Morcellation was performed on Day 0 (n=4), Day 4 (n=1), Day 6 (n=1), and Day 7 (n=3). The intervals were compared regarding the morcellation efficiency, beach ball presence, and pathology.

Results: The mean estimated prostate volume was 383 (range 330-528) mL; the median enucleation weight was 252 (interquartile range [IQR] 222, 342) g; and the median enucleation time was 83 (IQR 62, 100) min. The mean morcellation efficiency was 1.44 (SD 0.55) g/min on Day 0 and 13.69 (SD 2.46) g/min on day 7. The morcellation efficiency was 4.15 g/min and 10.50 g/min on Day 4 and Day 6, respectively, with significantly higher in the two-stage group compared to one-stage group (11.0 g/min vs. 1.5 g/min; p=0.014). Efficiency was strongly correlated with intervals (p<0.001); the incidences of beach balls were 100% (4/4) and 60% (3/5) in the immediate and two-stage surgery groups, respectively.

Conclusion: The efficiency of two-stage morcellation with reciprocating morcellators was highly related to the postoperative interval, with the maximum efficiency reached on Day 7.

Key words:  Holmium laser enucleation of the prostate    Reciprocating morcellator    Giant adenoma    Two-stage surgery
收稿日期:  2022-11-27           接受日期:  2023-04-26      出版日期:  2024-07-20      发布日期:  2024-08-13      整期出版日期:  2024-07-20
引用本文:    
. [J]. Asian Journal of Urology, 2024, 11(3): 423-428.
Fumiyasu Endo, Masaki Shimbo, Kenji Komatsu, Kazuhiro Ohwaki, Kazunori Hattori. Optimal interval for delayed retrieval surgery with reciprocating morcellators after enucleation of giant prostatic hyperplasia in holmium laser enucleation of the prostate. Asian Journal of Urology, 2024, 11(3): 423-428.
链接本文:  
http://www.ajurology.com/CN/10.1016/j.ajur.2023.04.005  或          http://www.ajurology.com/CN/Y2024/V11/I3/423
Parameter One-stage surgery (n=4) Two-stage surgery (n=5) p-Value
Age, year 77.5 (73.5, 78.5) 77.0 (72.0, 81.0) 0.902
Body mass index, kg/m2 23.5 (23.0, 24.1) 24.4 (24.2, 25.1) 0.221
Estimated prostate volume, mean (range), mL 373 (354-402) 391 (330-528) 1.000
Prostate-specific antigen, ng/mL 12.5 (6.3, 19.7) 8.2 (7.4, 9.7) 0.807
Total operating time, min 344 (266, 363) 155 (132, 155) 0.014
Enucleation time, min 80 (52, 99) 83 (74, 102) 0.389
Enucleated weight, g 228 (197, 255) 252 (220, 361) 0.462
Change in hemoglobin, g/dL ?3.1 (?3.8, ?2.0) ?2.3 (?3.6, ?1.1) 0.462
Hypothermia (<34 °C), n (%) 2 (50) 0 (0) 0.167
Continent recovery, mean (range), month 2.5 (1-3) 5.5 (1-15)a 0.617
Hospital length of stay, day 6.5 (5.0, 8.0) 10 (9, 11) 0.048
Morcellation efficiency, g/min 1.5 (1.0, 1.9) 11.0 (10.5, 14.4) 0.014
  
  
Case Interval to morcellation, day Enucleated weigh, g Enucleation time, min Enucleation efficiency, g/min Morcellation time, min Morcellation efficiency, g/min Beach ball
1 0 222 100 2.22 180 1.23 Present
2 0 171 62 5.52 226 0.76 Present
7 171 - - 14 12.21 None
3 7 432 74 5.84 30 14.40 None
4 7 220 102 2.16 14 15.71 Present
5 4 361 62 5.82 87 4.15 Present
6 0 234 98 2.39 131 1.79 Present
7 7 252 104 2.42 23 10.96 None
8 0 276 41 6.73 140 1.97 Present
9 6 210 83 2.53 20 10.50 Present
  
  
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