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Asian Journal of Urology, 2023, 10(2): 189-194    doi: 10.1016/j.ajur.2021.12.003
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Tunica albuginea versus buccal mucosa graft urethroplasty for anterior urethral stricture: A prospective randomised pilot study
Mohammad Shazib Faridia*(),Vikas Sharmab,Adittya K. Sharmac,Rahul Yadavc
aDivision of Urology, Department of Surgery, Hamdard Institute of Medical Sciences & Research and HAHC Hospital, New Delhi, India
bDepartment of Urology, Rajiv Gandhi Super Speciality Hospital, Tahirpur, Delhi, India
cDepartment of Urology, Apollomedics Super Speciality Hospital, Lucknow, Uttar Pradesh, India
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Abstract: 

Objective: The objective of the study was to compare the outcome of tunica albuginea urethroplasty (TAU) and buccal mucosa graft (BMG) urethroplasty for anterior urethral stricture.
Methods: Thirty patients who met the inclusion criteria were randomised into two groups: TAU (Group A) and BMG urethroplasty (Group B). Surgical outcome was evaluated with pre- and post-operative work-up involving retrograde urethrogram, voiding cystourethrogram, uroflowmetry, and urethroscopy. Patients were followed up till 1 year.
Results: Mean duration of surgery was statistically significant between two groups (p=0.0005). Maximum urine flow rate was comparable when compared between two groups (p=0.22) but statistically significant when compared pre- and post-operatively (p<0.001). At follow-up of 1 year, the successful outcomes were 80% in Group A and 87% in Group B. A total of five patients who had unsuccessful results required redo urethroplasty. Complications were minimal in both the groups.
Conclusion: TAU provides outcomes equivalent to those of BMG urethroplasty. TAU has less operative time, easy to perform, and beneficial in patients with poor oral hygiene.

Key words:  Buccal mucosa    Male urologic surgery    Tunica albuginea    Urethral stricture    Urethroplasty
收稿日期:  2020-10-15      修回日期:  2021-04-12      接受日期:  2021-09-07      出版日期:  2023-04-20      发布日期:  2023-05-24      整期出版日期:  2023-04-20
引用本文:    
. [J]. Asian Journal of Urology, 2023, 10(2): 189-194.
Mohammad Shazib Faridi,Vikas Sharma,Adittya K. Sharma,Rahul Yadav. Tunica albuginea versus buccal mucosa graft urethroplasty for anterior urethral stricture: A prospective randomised pilot study. Asian Journal of Urology, 2023, 10(2): 189-194.
链接本文:  
http://www.ajurology.com/CN/10.1016/j.ajur.2021.12.003  或          http://www.ajurology.com/CN/Y2023/V10/I2/189
  
  
  
  
Parameter Group Aa Group Bb p-Valuec
Age, mean±SD, year 39.26±11.61 41.46±7.88 0.54
Length of stricture, mean±SD, cm 4.24±1.03 4.25±1.21 0.98
Location of the stricture, n (%)
Penile urethra 3 (20.0) 2 (13.3) 0.62
Penobulbar urethra 4 (26.7) 4 (26.7) 1.00
Bulbar urethra 8 (53.3) 9 (60.0) 0.71
Qmaxd, mean±SD, mL/s (preoperative) 10.40±2.54 9.94±2.64 0.63
PVR, mean±SD, mL (preoperative) 67.13±14.29 66.40±12.14 0.88
Duration of stricture, mean±SD, month 10.53±2.77 10.46±1.98 0.93
Width of urethral plate, mean±SD, cm 3.66±0.19 3.70±0.17 0.93
Duration of surgerye, mean±SD, min 121.73±7.35 132.20±7.25 0.0005
Qmaxd, mean±SD, mL/s (postoperative) 29.24±1.96 30.24±2.37 0.22
  
Outcome Group Aa, n (%) Group Bb, n (%) p-Valuec
6 months 12 months 6 months 12 months 6 months 12 months
Success 13 (87) 12 (80) 14 (93) 13 (87) 1.00 1.00
Failure 2 (13) 3 (20) 1 (7) 2 (13) 1.00 1.00
  
  
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