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Asian Journal of Urology, 2023, 10(2): 177-181    doi: 10.1016/j.ajur.2021.10.003
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Radiofrequency ablation for renal tumours: A retrospective study from a tertiary centre
Mohammed Al-Zubaidia*(),Kennia Lottera,Martin Marshallb,Mikhail Lozinskiya
aDepartment of Urology, Royal Perth Hospital, Perth, Australia
bDepartment of Radiology, Royal Perth Hospital, Perth, Australia
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Abstract: 

Objective: This study aimed to evaluate the safety and efficacy outcomes of percutaneous radiofrequency ablation (RFA) for localised renal cell carcinoma (RCC) in a tertiary hospital patient who remained unfit for surgical intervention.
Methods: We retrospectively analysed survival outcomes for patients with biopsy proven RCC treated by RFA at Royal Perth Hospital between September 2009 and May 2018. Complication data were gathered for all patients that underwent renal RFA along with 2- and 5-year recurrence-free survival (RFS) rate and compared the outcomes with data from previous studies.
Results: A total of 69 patients (73 procedures) were eligible for the study, and those patients had biopsy-proven RCC with a minimum of 2-year follow-up. The complication rate was 8.2% (6/73) and local recurrence rate 9.6% (7/73). Two-year RFS is 95.7% and 5-year RFS is 78.8% on a median 3.82-year follow-up (interquartile range 1.90-5.75 years).
Conclusion: RFA performed at our centre was found to be safe and effective with low complication rates and durable RFS in line with expectations from existing research. Our study demonstrated that RFA is an alternative modality of treatment for small renal tumours in patients unfit for surgical approach.

Key words:  Radiofrequency ablation    Small renal tumour    Hydrodissection    Renal cell carcinoma
收稿日期:  2020-11-17      修回日期:  2021-04-05      接受日期:  2021-07-02      出版日期:  2023-04-20      发布日期:  2023-05-24      整期出版日期:  2023-04-20
引用本文:    
. [J]. Asian Journal of Urology, 2023, 10(2): 177-181.
Mohammed Al-Zubaidi,Kennia Lotter,Martin Marshall,Mikhail Lozinskiy. Radiofrequency ablation for renal tumours: A retrospective study from a tertiary centre. Asian Journal of Urology, 2023, 10(2): 177-181.
链接本文:  
http://www.ajurology.com/CN/10.1016/j.ajur.2021.10.003  或          http://www.ajurology.com/CN/Y2023/V10/I2/177
Patients details Value
Number of patients, n (%) 69 (100)
Male 41 (59.4)
Female 28 (40.6)
Age, median (range), year 68 (47-89)
Median follow-up period, year 6
  
Tumour characteristic Value
Size, median (range), cm 3.2 (1.2-5.2)
Size, n (%)
≤4 cm 69 (94.5)
>4 cm 4 (5.5)
Tumour location, n (%)
Left side 41 (56.2)
Right side 31 (42.5)
Pelvic kidney 1 (1.4)
Location in affected kidney, n (%)
Upper pole 13 (17.8)
Interpolar 33 (45.2)
Lower pole 27 (37.0)
  
Reason Value, n (%)
Comorbidities increasing the risk of surgery and/or anaesthesia 48 (65.8)
Solitary kidney 5 (6.8)
Recurrence 4 (5.5)
Patient preference 16 (21.9)
Multiple tumours same kidney 1 (1.4)
  
Complication Value, n (%)
Haematoma 4 (5.5)
Contrast extravasation 1 (1.4)
Pneumothorax 1 (1.4)
Total 6 (8.2)
  
Patient number Tumour size prior to first RFA, mm Tumour size upon recurrence, mm Modality of treatment Interval Histology
1 20 20 RFA 2 years Clear cell RCC
2 30 22 RFA 4 months Clear cell RCC
3 33 21 RFA 4 years Clear cell RCC
4 38 42 RFA 2 years Clear cell RCC
5 16 20 Partial nephrectomy 6 months Clear cell RCC
6 21 17 Radical nephrectomy 3 years Clear cell RCC
7 30 15 Partial nephrectomy 13 months Clear cell RCC
  
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