Priapism secondary to chronic myeloid leukemia (CML) is rarely observed in the clinic. Here, we present an 18-year-old patient with priapism for over 72 h due to hyperleukocytosis. Emergent interventions such as therapeutic aspiration and intracorporal injection of phenylephrine failed before a surgical corpora cavernosa-corpus spongiosum shunt was inserted to relieve symptoms. During hospitalization, bone marrow aspiration confirmed the diagnosis of CML.
. [J]. Asian Journal of Urology, 2019, 6(4): 373-376.
Min Qu,Xin Lu,Lei Wang,Zhiyong Liu,Yinghao Sun,Xu Gao. Priapism secondary to chronic myeloid leukemia treated by a surgical cavernosa-corpus spongiosum shunt: Case report. Asian Journal of Urology, 2019, 6(4): 373-376.
Initiated by cavernosal aspiration/irrigation and injection of epinephrine, followed by penileprosthesis surgery
Erectile dysfunction followed by penile prosthesis implantatio
Hazra et al. [10], 2013
1
14
226.9
Cavernosal aspiration, irrigation and phenylepinephrine injection
Maintaining erection
Veljkovic et al. [11], 2012
1
16
320
Leukapheresis
No follow-up
Tazl [12], 2009
1
33
400
Cavernosa aspiration and epinephrine irrigation
No erectile dysfunction
Gupta et al. [13], 2009
1
12
346
Administration of terbutaline
No follow-up
[1]
Van der Horst C, Stuebinger H, Seif C, Melchior D, Martinez- Portillo FJ, Juenemann KP . Priapismdetiology, pathophysiology and management. Int Braz J Urol 2003; 29:391-400.
[2]
Burnett AL, Bivalacqua TJ . Priapism: new concepts in medical and surgical management. Urol Clin North Am 2011; 38:185-94.
[3]
Diallo D, Zaitouna M, Alsaid B, Quillard J, Droupy S, Benoit G . What is the origin of the arterial vascularization of the corpora cavernosa? A computer-assisted anatomic dissection study. J Anat 2013; 223:489-94.
[4]
Ergenc H, Varim C, Karacaer C, Cekdemir D . Chronic myeloid leukemia presented with priapism: effective management with prompt leukapheresis. Niger J Clin Pract 2015; 18:828-30.
[5]
Rodgers R, Latif Z, Copland M . How I manage priapism in chronic myeloid leukaemia patients. Br J Haematol 2012; 158:155-64.
[6]
Kandel GL, Bender LI, Grove JS . Pulmonary embolism: a complication of corpus-saphenous shunt forpriapism. J Urol 1968; 99:196-7.
[7]
Kurosawa H, Tanizawa A, Tono C, Watanabe A, Shima H, Ito M , et al. Leukostasis in children and adolescents with chronic myeloid leukemia: Japanese Pediatric Leukemia/Lymphoma Study Group. Pediatr Blood Cancer 2016; 63:406-11.
[8]
Nerli RB, Magdum PV, Hiremath SC, Patil AY, Pai SV, Handigund RS , et al. Priapismda rare presentation in chronic myeloid leukemia: Case report. Urol Case Rep 2016; 4:8-10.
[9]
Shaeer OK, Shaeer KZ, AbdelRahman IF, El-Haddad MS, Selim OM . Priapism as a result of chronic myeloid leukemia: case report, pathology, and review of the literature. J Sex Med 2015; 12:827-34.
[10]
Hazra SP, Priyadarshi V, Gogoi D, Sharma PK, Pal DK, Chakraborty SC . Pediatric priapism: a rare first manifestation of leukemia. APSP J Case Rep 2013; 4:39.
[11]
Veljkovic D, Kuzmanovic M, Micic D, ?erbi?-Nonkovi? O . Leukapheresis in management hyperleucocytosis induced complications in two pediatric patients with chronic myelogenous leukemia. Transfus Apher Sci 2012; 46:263-7.
[12]
Tazi I . Priapism as the first manifestation of chronic myeloid leukemia. Ann Saudi Med 2009; 29:412.
[13]
Gupta A, Seth T, Gupta A . Successful use of terbutaline in persistent priapism in a12-year-old boy with chronic myeloid leukemia. Pediatr Hematol Oncol 2009; 26:70-3.
