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Asian Journal of Urology, 2017, 4(3): 185-190    doi: 10.1016/j.ajur.2017.06.002
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Medical therapy for clinical benign prostatic hyperplasia:a1 Antagonists, 5a reductase inhibitors and their combination
Cheuk Fan Shum, Weida Lau, Chang Peng Colin Teo
Department of Urology, Khoo Teck Puat Hospital, Singapore
Medical therapy for clinical benign prostatic hyperplasia:a1 Antagonists, 5a reductase inhibitors and their combination
Cheuk Fan Shum, Weida Lau, Chang Peng Colin Teo
Department of Urology, Khoo Teck Puat Hospital, Singapore
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摘要 Medical therapy for clinical benign prostatic hyperplasia (BPH) has advanced significantly in the last 2 decades. Many new α1 antagonists and 5α reductase inhibitors (5ARi) are now commercially available. The practicing urologist must decide on the most appropriate medication for his patients, taking into consideration various factors like efficacy, dosing regime, adverse effects, cost, patient's socioeconomic background, expectations, drug availability and his own clinical experience. The use of combination therapy added further to the complexity in clinical judgment when prescribing. We highlight some of the key points in prescribing α1 antagonists, 5ARi and their combination, based on our viewpoints and experience as urologists in an Asian clinical setting.
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Cheuk Fan Shum
Weida Lau
Chang Peng Colin Teo
关键词:  5α Reductase inhibitors  Adrenergic α1 receptor antagonists  Drug therapy  Combination  Prostatic hyperplasia    
Abstract: Medical therapy for clinical benign prostatic hyperplasia (BPH) has advanced significantly in the last 2 decades. Many new α1 antagonists and 5α reductase inhibitors (5ARi) are now commercially available. The practicing urologist must decide on the most appropriate medication for his patients, taking into consideration various factors like efficacy, dosing regime, adverse effects, cost, patient's socioeconomic background, expectations, drug availability and his own clinical experience. The use of combination therapy added further to the complexity in clinical judgment when prescribing. We highlight some of the key points in prescribing α1 antagonists, 5ARi and their combination, based on our viewpoints and experience as urologists in an Asian clinical setting.
Key words:  5α Reductase inhibitors    Adrenergic α1 receptor antagonists    Drug therapy    Combination    Prostatic hyperplasia
收稿日期:  2016-10-04      修回日期:  2017-05-31           出版日期:  2017-07-01      发布日期:  2017-08-26      整期出版日期:  2017-07-01
通讯作者:  Cheuk Fan Shum,E-mail address:shum.cheuk.fan@alexandrahealth.com.sg.    E-mail:  shum.cheuk.fan@alexandrahealth.com.sg
引用本文:    
Cheuk Fan Shum, Weida Lau, Chang Peng Colin Teo. Medical therapy for clinical benign prostatic hyperplasia:a1 Antagonists, 5a reductase inhibitors and their combination[J]. Asian Journal of Urology, 2017, 4(3): 185-190.
Cheuk Fan Shum, Weida Lau, Chang Peng Colin Teo. Medical therapy for clinical benign prostatic hyperplasia:a1 Antagonists, 5a reductase inhibitors and their combination. Asian Journal of Urology, 2017, 4(3): 185-190.
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http://www.ajurology.com/CN/10.1016/j.ajur.2017.06.002  或          http://www.ajurology.com/CN/Y2017/V4/I3/185
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