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Asian Journal of Urology, 2016, 3(1): 39-43    doi: 10.1016/j.ajur.2015.10.002
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Can intravesical prostatic protrusion predict bladder outlet obstruction even in men with good flow?
Alvin Leea, Han Jie Leea, Kok Bin Limb, Hong Hong Huanga, Henry Hoa, Keong Tatt Fooa
a Department of Urology, Singapore General Hospital, Singapore;
b Urology Centre, Raffles Hospital, Singapore
Can intravesical prostatic protrusion predict bladder outlet obstruction even in men with good flow?
Alvin Leea, Han Jie Leea, Kok Bin Limb, Hong Hong Huanga, Henry Hoa, Keong Tatt Fooa
a Department of Urology, Singapore General Hospital, Singapore;
b Urology Centre, Raffles Hospital, Singapore
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摘要 Objective: Men with benign prostate hyperplasia (BPH) with good urinary flow may still have bladder outlet obstruction (BOO). Intravesical prostatic protrusion (IPP) has been shown to be able to predict BOO. We aim to investigate the use of IPP to predict BOO in men with good urinary flow.
Methods: One hundred and fourteen consecutive men (>50 years old) presenting with lower urinary tract symptoms suggestive of BPH were recruited in 2001 and 2002. They were evaluated with serum prostate specific antigen (PSA), uroflowmetry and transabdominal ultrasound measurement of IPP and prostate volume (PV). Pressure-flow urodynamic studies were performed on all men and BOO was defined by BOO index > 40. Men with Qmax ≥12.0 mL/s were considered to have good flow.
Results: Among the 114 men, 61 patients had good urinary flow. Their median age, PV and Qmax were 66 years, 32.9 mm3 and 14.5 mL/s respectively. 14/61 (23.0%) patients had BOO and their distribution of IPP were as follows: Grade 1 e 0/20 (0%) obstructed, Grade 2-6/22 (27.3%) and Grade 3-8/19 (42.1%). Sensitivity of Grade 2/3 IPP for BOO was 100% while specificity of Grade 3 IPP was 76.6%. The area-under-curve (AUC) for IPP was greater than that for PV (0.757 vs. 0.696).
Conclusion: Even in men with good flow, high grades of IPP were more likely to have BOO and hence, may be a useful adjunct to predict BOO.
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Alvin Lee
Han Jie Lee
Kok Bin Lim
Hong Hong Huang
Henry Ho
Keong Tatt Foo
关键词:  Male  Prostate hyperplasia  Pathology  Ultrasonography  Urinary bladder  Urodynamics    
Abstract: Objective: Men with benign prostate hyperplasia (BPH) with good urinary flow may still have bladder outlet obstruction (BOO). Intravesical prostatic protrusion (IPP) has been shown to be able to predict BOO. We aim to investigate the use of IPP to predict BOO in men with good urinary flow.
Methods: One hundred and fourteen consecutive men (>50 years old) presenting with lower urinary tract symptoms suggestive of BPH were recruited in 2001 and 2002. They were evaluated with serum prostate specific antigen (PSA), uroflowmetry and transabdominal ultrasound measurement of IPP and prostate volume (PV). Pressure-flow urodynamic studies were performed on all men and BOO was defined by BOO index > 40. Men with Qmax ≥12.0 mL/s were considered to have good flow.
Results: Among the 114 men, 61 patients had good urinary flow. Their median age, PV and Qmax were 66 years, 32.9 mm3 and 14.5 mL/s respectively. 14/61 (23.0%) patients had BOO and their distribution of IPP were as follows: Grade 1 e 0/20 (0%) obstructed, Grade 2-6/22 (27.3%) and Grade 3-8/19 (42.1%). Sensitivity of Grade 2/3 IPP for BOO was 100% while specificity of Grade 3 IPP was 76.6%. The area-under-curve (AUC) for IPP was greater than that for PV (0.757 vs. 0.696).
Conclusion: Even in men with good flow, high grades of IPP were more likely to have BOO and hence, may be a useful adjunct to predict BOO.
Key words:  Male    Prostate hyperplasia    Pathology    Ultrasonography    Urinary bladder    Urodynamics
收稿日期:  2015-07-05      修回日期:  2015-09-16           出版日期:  2016-01-01      发布日期:  2016-01-29      整期出版日期:  2016-01-01
通讯作者:  Henry Ho    E-mail:  henry.ho.s.s@sgh.com.sg
引用本文:    
Alvin Lee, Han Jie Lee, Kok Bin Lim, Hong Hong Huang, Henry Ho, Keong Tatt Foo. Can intravesical prostatic protrusion predict bladder outlet obstruction even in men with good flow?[J]. Asian Journal of Urology, 2016, 3(1): 39-43.
Alvin Lee, Han Jie Lee, Kok Bin Lim, Hong Hong Huang, Henry Ho, Keong Tatt Foo. Can intravesical prostatic protrusion predict bladder outlet obstruction even in men with good flow?. Asian Journal of Urology, 2016, 3(1): 39-43.
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http://www.ajurology.com/CN/10.1016/j.ajur.2015.10.002  或          http://www.ajurology.com/CN/Y2016/V3/I1/39
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